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Suboxone strips, sometimes referred to as Suboxone film, is a dissolvable strip containing the opioid buprenorphine and naloxone, the active ingredients in Suboxone. The strips/films can be administered sublingually (under the tongue) or placed inside the cheek where they rapidly dissolve.
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Suboxone is an opioid drug that is commonly used for the relief of withdrawal symptoms related to the use of more powerful opioids such as heroin. It can also be used for the treatment of moderate in low dosages.
The Buprenorphine that is present in Suboxone is a partial opioid agonist – in other words, it works in the brain in the same manner that other, stronger opioids do, but produces milder effects.
Naloxone, also present in Suboxone, prevents the medication from being abused. This combination makes Suboxone an excellent medication to treat opioid addiction or ease pain with less risk of dependency or misuse.
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Buy Suboxone strips Online. Suboxone is a brand name prescription medication used to treat opioid use disorder. It is used in medication-assisted treatment (MAT) to help people reduce or quit their use of heroin or other opiates, such as pain relievers like morphine if used as directed. It contains a combination of buprenorphine and naloxone. The buprenorphine is an opioid medication, but it eases cravings by not providing the same intense highs as other opiates.
Naloxone binds to opioid receptors partially rather than fully, and the blocking effect of the drug lasts for around an hour or two. There also are unique properties of buprenorphine, and this makes it much longer-lasting than many other opiates. In fact, the effects of buprenorphine can last as long as 24 hours.
How To Take Suboxone Strips
- There are two ways to administer Suboxone strips- sublingual or through the insides of the cheek. Moreover, the films can be placed under the tongue or on either the left or right side of the inside of the cheek. Either way, the strip is left to dissolve easily without further concern.
- The important thing to remember regarding Suboxone strips is they should be dissolved completely. It cannot be chewed, swallowed, or cut to get the expected potency.
- Using this sublingual administration, people who need help to recover from opioid dependence don’t need to take Suboxone in form anymore. One of the common disadvantages of taking the drug as a pill is the process is not as discreet compared to the film and also may have a greater potential for abuse.
Interaction with other medicinal products
Suboxone should not be taken together with:
• alcoholic drinks or medicines containing alcohol, as alcohol increases the sedative effect of buprenorphine (see section 4.7).
Suboxone should be used cautiously when co-administered with:
o benzodiazepines: This combination may result in death due to respiratory depression of central origin. Therefore, dosages must be limited and this combination must be avoided in cases where there is a risk of misuse. Patients should be warned that it is extremely dangerous to self-administer non-prescribed benzodiazepines while taking this product, and should also be cautioned to use benzodiazepines concurrently with this product only as directed by their physician (see section 4.4).
o other central nervous system depressants, other opioid derivatives (e.g. methadone, analgesics and antitussives), certain antidepressants, sedative H1-receptor antagonists, barbiturates, anxiolytics other than benzodiazepines, neuroleptics, clonidine and related substances: these combinations increase central nervous system depression. The reduced level of alertness can make driving and using machines hazardous.
o Furthermore, adequate analgesia may be difficult to achieve when administering a full opioid agonist in patients receiving buprenorphine/naloxone. Therefore the potential to overdose with a full agonist exists, especially when attempting to overcome buprenorphine partial agonist effects, or when buprenorphine plasma levels are declining.
o naltrexone and nalmefene are opioid antagonists that can block the pharmacological effects of buprenorphine. Co-administration during buprenorphine/naloxone treatment is contraindicated due to the potentially dangerous interaction that may precipitate a sudden onset of prolonged and intense opioid withdrawal symptoms (see section 4.3).
o CYP3A4 inhibitors: an interaction study of buprenorphine with ketoconazole (a potent inhibitor of CYP3A4) resulted in increased Cmax and AUC (area under the curve) of buprenorphine (approximately 50 % and 70 % respectively) and, to a lesser extent, of norbuprenorphine. Patients receiving Suboxone should be closely monitored, and may require dose-reduction if combined with potent CYP3A4 inhibitors (e.g. protease inhibitors like, nelfinavir or indinavir or azole antifungals such as ketoconazole or itraconazole, ritonavir macrolide antibiotics).
o CYP3A4 inducers: Concomitant use of CYP3A4 inducers with buprenorphine may decrease buprenorphine plasma concentrations, potentially resulting in sub-optimal treatment of opioid dependence with buprenorphine. It is recommended that patients receiving buprenorphine/naloxone should be closely monitored if inducers (e.g. phenobarbital, carbamazepine, phenytoin, rifampicin) are co-administered. The dose of buprenorphine or the CYP3A4 inducer may need to be adjusted accordingly.
o the concomitant use of monoamine oxidase inhibitors (MAOI) might produce exaggeration of the effects of opioids, based on experience with morphine.
SUBOXONE sublingual film may not be right for you. Before taking SUBOXONE sublingual film, tell your doctor if you:
· Have liver or kidney problems
· Have trouble breathing or lung problems
· Have an enlarged prostate gland (men)
· Have a head injury or brain problem
· Have problems urinating
· Have a curve in your spine that affects your breathing
· Have gallbladder problems
· Have adrenal gland problems
· Have Addison’s disease
· Have low thyroid (hypothyroidism)
· Have a history of alcoholism
· Have mental problems such as hallucinations (seeing or hearing things that are not
· Have any other medical condition
· Are pregnant or plan to become pregnant. If you take SUBOXONE sublingual film while pregnant, your baby may have signs of opioid withdrawal at birth. Neonatal opioid withdrawal syndrome (NOWS) is an expected and treatable outcome of prolonged use of opioids during pregnancy. Talk to your doctor if you are pregnant or plan to become pregnant.
· Are breastfeeding or plan to breastfeed. SUBOXONE sublingual film can pass into your milk and may harm your baby. Talk to your doctor about the best way to feed your baby if you take SUBOXONE sublingual film. Monitor your baby for increased sleepiness and breathing problems.
Tell your doctor about all the medicines you take, including prescription and over‐the‐counter medicines, vitamins, and herbal supplements. SUBOXONE sublingual film may affect the way other medicines work, and other medicines may affect how SUBOXONE sublingual film works. Some medicines may cause serious or life‐threatening medical problems when taken with SUBOXONE sublingual film.
Sometimes the doses of certain medicines and SUBOXONE sublingual film may need to be changed if used together. Do not take any medicine while using SUBOXONE until you have talked with your doctor. Your doctor will tell you if it is safe to take other medicines while you are taking SUBOXONE sublingual film.
Suboxone Strips Side Effects
Side effects of using Suboxone strips are identical to those of Suboxone in pill form. While Suboxone is indicated to treat severe addictions, it’s also a psychoactive drug, so medical professionals must be particularly careful when prescribing it. In the short term, users typically feel relaxed and calm. The drug’s effects include a feeling of peacefulness that can endure as long as two days.
Still, some people may abuse it which may result in side effects, such as the following:
To avoid adverse side effects of Suboxone strips, patients should only use it as directed and in combination with a comprehensive addiction treatment plan.
Unfortunately, some people abuse the drug for non-medical purposes while not participating in a rehab program. If Suboxone is taken in conjunction with the abuse of other depressants such as alcohol or benzodiazepines, side effects can be much more severe. Breathing problems and even death can result from traumatic central nervous system depression.
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